Differential testing is a well-known technique in compiler testing. In our recent research project, we use this approach to random-test (aka fuzz) Simulink, the popular model-based design tool by MathWorks. Check out the project homepage for an early prototype implementation of our testing scheme which randomly generates (valid) Simulink models and applies differential testing technique to find bugs in Simulink. The project is open source and we welcome new contributors!
Anything but "Hacking" 